Combinatorial and sequential targeted therapy in mRCC

Kidney cancer. Principles and practice. Second edition. Primo N. Lara, Jr. Eric Jonasch (Editors). Springer International Publishing (2015)


  1. Introduction
  2. Combination therapies
    • Combining targeted therapies
    • Combining targeted agents and novel drugs
    • Combining targeted agents and novel immunotherapies
    • Combining targeted agents and traditional immunotherapies
    • Combining targeted agents and chemotherapy
  1. Sequential targeted therapies
    • Cytokines and sequential targeted therapies
    • Sequential use of targeted therapies
    • VEGF inhibitors: TKIs and bevacizumab
    • Sequencing regimens with VEGFi and mTORi
    • Conclusions regarding sequential therapies
  1. Future directions
  2. References

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