The metabolic basis of kidney cancer

Primo N. Lara, Jr. Eric Jonasch (Editors). kidney cancer (2 ed). Springer International Publishing (2015) → Русский

  1. Introduction

  2. Overview of metabolism in cancer

    • Glycolysis, the Krebs cycle, and the Warburg effect

    • Drivers of the Warburg effect in human cancer

    • Glutaminolysis and reductive carboxylation

  1. Metabolic alterations in kidney cancer

    • Kidney cancers harboring mutations in Krebs cycle enzyme genes

    • Von Hippel–Lindau syndrome and clear cell renal cell carcinoma

    • Hereditary papillary renal cell carcinoma and type 1 papillary renal cell carcinoma

    • Birt–Hogg–Dubé syndrome and chromophobe renal cell carcinoma

    • Tuberous sclerosis complex

    • TFE-fusion renal cell carcinoma

    • Cowden’s syndrome

  1. Targeting aberrant metabolic pathways in kidney cancer

  2. Summary

  3. References