Primo N. Lara, Jr. Eric Jonasch (Editors). kidney cancer (2 ed). Springer International Publishing (2015) → Русский
Over the past two decades, the complex heterogeneity underlying cancers arising in the kidney has become increasingly apparent. By studying familial kidney cancer syndromes, a variety of genetic and molecular alterations have been identified as key drivers in these tumors. As with many other malignancies, altered metabolism appears to be a common theme underlying the different subtypes of RCC. Although significant advances have been made in our ability to manage more common forms of kidney cancer, durable responses and cures remain elusive. It is hoped that elucidation of the complex metabolic networks operating in these tumors will inform future design of therapeutic strategies and help consolidate current gains in the battle against kidney cancer.