Mesenchymal stem cells

Encyclopedia of Cancer (2015)




A type of stem cell found in bone marrow (marrow stromal cells) and many other locations, e.g., adipose tissue. Defined by their ability to adhere to plastic when cultured, and of trilineage differentiation into fat, cartilage, and bone. Found to be highly malleable and can be switched to many other different cell types.

Possess an extensive proliferative potential and ability to differentiate into various cell types, including osteocytes, adipocytes, chondrocytes, myocytes, cardiomyocytes, and neurons.


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