Interaction of immune and cancer cells (2014) | ПРЕЦИЗИОННАЯ ОНКОЛОГИЯ

Interaction of immune and cancer cells (2014)

Klink (ed.), Interaction of Immune and Cancer Cells. Springer-Verlag (2014)


  • Immune cells within the tumor microenvironment
    • Introduction
    • Roles of immune system in tumorigenesis
    • Tumor-promoting immune cell types in the microenvironment of primary tumor
      • Tumor-associated macrophages (IL-10high IL-12low IL-1rahigh and IL-1 decoyRhigh)
      • Myeloid-derived suppressor cells (CD11b+ Gr1+)
      • Dendritic cells
      • Tumor-infiltrating t cells
      • Regulatory T cells (CD4+ CD25+ FOXP3+)
      • Mast Cells (c-KIT+)
    • Conclusions and future remarks
    • References
  • Tumor–stroma interaction and cancer progression
  • The Role of tumor-associated macrophages (TAMs) in tumor progression
  • Cancer immunotherapy via dendritic cells
  • Myeloid-derived suppressor cells and tumor growth
  • Tumor-infiltrating lymphocytes and their role in solid tumor progression
  • Polymorphonuclear neutrophils and tumors: friend or foe?
  • Cancer immunoediting: elimination, equilibrium, and immune escape in solid tumors
  • Adoptive T-cell immunotherapy: perfecting self-defenses
  • Monoclonal antibodies to CTLA-4 with focus on ipilimumab
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