1. Isolation and characterization of human embryonic stem cells and future applications in tissue engineering therapies

Principles of stem cell biology and cancer: future applications and therapeutics. Edited by T. Regad, T. J. Sayers and R. C. Rees. John Wiley & Sons (2015)

Part I. Stem Cells


Derivation of human embryonic stem cells from the ICM »

Basic characterization of hESCs »

Stem cell quality and culture adaptation with reference to cancer »

1.3.2.1. Imprinting and XCI

1.3.2.2. Methylation pattern

1.3.2.3. Histone modifications

1.3.3. hESC culture adaptation with reference to cancer (genomic and epigenetic)

1.3.3.1. Impact of hESC culture-induced genomic and epigenetic changes in differentiated cells

1.4. Future applications in tissue-engineering therapies »

      1.5. Conclusions

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