Regulation of breast CSCs by MSCs in the metastatic niche

Principles of stem cell biology and cancer: future applications and therapeutics. Edited by T. Regad, T. J. Sayers and R. C. Rees. John Wiley & Sons (2015)

Part II. Cancer stem cells


Introduction

Tumour microenvironment and CSCs

Isolation and identification of MSCs

Plasticity and the differentiation potential of MSCs

The role of MSCs in breast cancer

Induction of EMT and expansion of breast CSCs by MSCs

EMT and MET CSC plasticity in migration and metastasis

Signalling crosstalk between MSCs and breast CSCs

Conclusions

References


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