Oxford American handbook of oncology. Second Edition. Oxford University Press (2015)

Radiation oncology is a medical specialty that uses ionizing radiation to treat malignancies and a few specific benign diseases. Radiation was first used to treat cancer only one year after the discovery of x-rays, and significant technologic advances have been made in the past century. It is now used in more than 50% of all patients with cancer.

Historical perspective

Important dates in the history of radiation oncology

As a modality to treat cancer, radiation therapy can be used in several different ways:

  • Definitive treatment with or without chemotherapy, e.g., head and neck cancer, lung cancer, prostate cancer
  • Adjuvant treatment after completion of primary treatment, e.g., breast cancer, lymphoma
  • Neoadjuvant treatment induces tumor regression prior to definitive therapy, e.g., rectal cancer, sarcoma
  • Palliative treatment for symptom relief, e.g., brain or bone metastases, bronchial obstruction
1896 Discovery of x-rays by Wilhelm Roentgen
1898 Discovery of radium by Marie and Pierre Curie
1899 Treatment of skin cancer with x-rays
1915 Treatment of cervical cancer with radium implant
1934 Dose fractionation principles proposed by Regaud and Coutard
1950s External radiotherapy using radioactive cobalt (1 MV)
1960s Linear accelerators capable of megavoltage x-rays (4–25 MV)
1990s Three-dimensional planning using CT imaging
2000s Intensity-modulated radiotherapy and proton beam therapy



Добавить комментарий

Войти с помощью: 

Ваш e-mail не будет опубликован. Обязательные поля помечены *