Oxford American handbook of oncology. Second Edition. Oxford University Press (2015)
- Surgical resection is integral in the treatment of most patients with solid tumors.
- For some tumors (or certain stages of tumors), surgery alone is the treatment of choice; for others, surgery is a component of multidisciplinary care that may also include either induction or adjuvant therapy.
- Surgical approaches may be implemented with three goals in the management of cancer patients:
- Diagnosis and staging
- Curative intent
- In general, the goals of surgical resection for curative intent include complete resection of the primary tumor (with negative margins) and adequate intraoperative staging, depending on the tumor type.
- There is also a role, in certain tumors, for prophylactic surgery.
- For example, this surgery might be used for familial polyposis coli colon cancer in the patient who is known to be a BRCA1 gene carrier (breast cancer), and in some of the MEN syndromes (thyroid cancer).