Принципы и практика онкологии

Part I. Molecular biology of cancer

  1. The cancer genome
  2. Molecular methods in cancer
  3. Hallmarks of cancer: an organizing principle for cancer medicine
  4. Microbiome and cancer
  5. Cancer susceptibility syndromes

Part II. Etiology and epidemiology of cancer

Section 1. Etiology of cancer

  1. Tobacco
  2. Oncogenic viruses
  3. Inflammation
  4. Chemical factors
  5. Physical factors
  6. Dietary factors
  7. Obesity and physical activity

Section 2. Epidemiology of cancer

  1. Epidemiologic methods
  2. Global cancer incidence and mortality

Part III. Cancer therapeutics

  1. Precision medicine in oncology
  2. Essentials of radiation therapy
  3. Cancer immunotherapy
  4. Pharmacokinetics and pharmacodynamics of anticancer drugs
  5. Pharmacogenomics
  6. Alkylating agents
  7. Platinum analogs
  8. Antimetabolites
  9. Topoisomerase-interacting agents
  10. Antimicrotubule agents
  11. Kinase inhibitors as anticancer drugs
  12. Histone deacetylase inhibitors and demethylating agents
  13. Proteasome inhibitors
  14. Poly(ADP-ribose) polymerase inhibitors for tumors with defects in DNA repair
  15. Miscellaneous chemotherapeutic agents
  16. Hormonal agents
  17. Monoclonal antibodies
  18. Immunotherapy agents

Part IV. Cancer prevention and screening

  1. Tobacco use and the cancer patient
  2. Role of surgery in cancer prevention
  3. Cancer risk.reducing agents
  4. Prophylactic cancer vaccines
  5. Cancer screening
  6. Genetic counseling

Part V. Practice of oncology

  1. Design and analysis of clinical trials
  2. Assessment of clinical response
  3. Vascular access
  4. Endoscopic and robotic surgery
  5. Tumor biomarkers

Section 1. Cancer of the head and neck

  1. The molecular biology of head and neck cancers
  2. Cancer of the head and neck
  3. Rehabilitation after treatment of head and neck cancer

Section 2. Cancer of the thoracic cavity

  1. The molecular biology of lung cancer
  2. Non-small-cell lung cancer
  3. Small cell and neuroendocrine tumors of the lung
  4. Neoplasms of the mediastinum

Section 3. Cancers of the gastrointestinal tract

  1. Molecular biology of the esophagus and stomach
  2. Cancer of the esophagus
  3. Рак желудка
  4. The molecular biology of pancreas cancer
  5. Cancer of the pancreas
  6. Молекулярная биология рака печени
  7. Cancer of the liver
  8. Cancer of the biliary tree
  9. Small bowel cancer
  10. Гастроинтестинальная стромальная опухоль
  11. Молекулярная биология колоректального рака
  12. Cancer of the colon
  13. Cancer of the rectum
  14. Cancer of the anal region

Section 4. Cancers of the genitourinary system

  1. Molecular biology of kidney cancer
  2. Cancer of the kidney
  3. Молекулярная биология рака мочевого пузыря
  4. The molecular biology of prostate cancer
  5. Cancer of the prostate
  6. Cancer of the urethra and penis
  7. Cancer of the testis

Section 5. Gynecologic cancers

  1. Molecular biology of gynecologic cancers
  2. Cancer of the uterine body
  3. Gestational trophoblastic neoplasia
  4. Ovarian cancer

Section 6. Cancer of the breast

  1. Молекулярная биология рака молочной железы
  2. Malignant tumors of the breast

Section 7. Cancer of the endocrine system

  1. Molecular biology of endocrine tumors
  2. Thyroid tumors
  3. Parathyroid tumors
  4. Adrenal tumors
  5. Pancreatic neuroendocrine tumors
  6. Carcinoid tumors and the carcinoid syndrome
  7. Multiple endocrine neoplasia

Section 8. Sarcomas of soft tissue and bone

  1. Молекулярная биология сарком
  2. Soft tissue sarcoma
  3. Sarcomas of bone

Section 9. Cancers of the skin

  1. Cancer of the skin
  2. Molecular biology of cutaneous melanoma
  3. Cutaneous melanoma

Section 10. Neoplasms of the central nervous system

  1. Molecular biology of central nervous system tumors
  2. Neoplasms of the central nervous system

Section 11. Cancers in adolescents and young adults

  1. Adolescents and young adults with cancer

Section 12. Lymphomas in adults

  1. Molecular biology of lymphoma
  2. Non-hodgkin lymphoma
  3. Cutaneous lymphomas
  4. Primary central nervous system lymphoma

Section 13. Leukemias and plasma cell tumors

  1. Molecular biology of acute leukemias
  2. Management of acute leukemias
  3. Molecular biology of chronic leukemias
  4. Chronic myeloid leukemia
  5. Chronic lymphocytic leukemias
  6. Myelodysplastic syndromes
  7. Plasma cell neoplasms

Section 14. Other cancers

  1. Cancer of unknown primary
  2. Benign and malignant mesothelioma
  3. Peritoneal metastases and peritoneal mesothelioma
  4. Intraocular melanoma

Section 15. Oncologic emergencies

  1. Superior vena cava syndrome
  2. Increased intracranial pressure
  3. Spinal cord compression
  4. Metabolic emergencies

Section 16. Treatment of metastatic cancer

  1. Metastatic cancer to the brain
  2. Metastatic cancer to the lung
  3. Metastatic cancer to the liver
  4. Metastatic cancer to the bone
  5. Malignant pleural and pericardial effusions
  6. Malignant ascites
  7. Paraneoplastic syndromes

Section 17. Stem cell transplantation

  1. Autologous hematopoietic cell transplantation
  2. Allogeneic stem cell transplantation

Section 18. Management of adverse effects of treatment

  1. Infections in the cancer patient
  2. Neutropenia and thrombocytopenia
  3. Nausea and vomiting
  4. Diarrhea and constipation
  5. Oral complications
  6. Pulmonary toxicity
  7. Cardiac toxicity
  8. Hair loss and other hair changes
  9. Gonadal dysfunction
  10. Fatigue
  11. Second cancers
  12. Neurocognitive effects
  13. Cancer survivorship

Part VI. Palliative and alternative care

Section 1. Supportive care and quality of life

  1. Management of cancer pain
  2. Nutrition support
  3. Sexual problems
  4. Psychological issues
  5. Communicating news to the cancer patient
  6. Specialized care of the terminally ill
  7. Rehabilitation of the cancer patient

Section 2. Complementary, alternative, and integrative therapies

  1. Complementary, alternative, and integrative therapies in cancer care