Abbreviations

Resistance of cancer cells to CTL-mediated immunotherapyResistance to targeted anti-cancer therapeutics. Benjamin Bonavida, Salem Chouaib (Eds). Springer International Publishing Switzerland (2015)


ABC — ATP-binding cassette

ADAM — A disintegrin and metalloprotease

APC — Adenomatosis polyposis coli

APCs — Antigen presenting cells

APM — Antigen processing machinery

B7-H1, 3, 4 — B7 homolog family members

BMP — Bone morphogenetic protein

CEA — Carcinoembryonic antigen

CK1 — Casein kinase 1

COA-1 — Colon antigen-1

CRC — Colorectal cancer

CSC — Cancer stem cells

CSL — CBF1/Su(H)/Lag-1

CXCR-4 — C-X-C chemokine receptor type 4

EMT — Epithelial-to-mesenchymal transition

Ep-CAM — Epithelial cell adhesion molecule

EphB — Ephrin B

ESC — Embryonic stem cells

FZ — Frizzled

GBM — Glioblastoma multiforme

GDF-15 — Growth differentiation factor 15

Gp100 — Glycoprotein 100

GS — γ-Secretase

GSK3 — Glycogen synthase kinase 3

Hh — Hedgehog

HLA — Human leukocyte antigen

IDO Indoleamine — 2,3-dioxigenase

IFN — Interferon

IL-10 — Interleukin-10

IL-13α2 — α2 chain of IL-13 receptor

IL-4 — Interleukin-4

LRP — Low-density-lipoprotein-related protein5/6

M — Mastermind-like protein 1

MAA — Melanoma associated antigen

MAGE — Melanoma-associated antigen gene

MART-1 — Melanoma antigen recognized by T cells

MDSC — Myeloid derived suppressor cell

Melan-A Protein melan-A, see also MART-1

MHC — Major histocompatibility complex

MSC — Mesenchymal stem cell

MUC-1 — Mucin 1

NKG2D — Natural killer group 2, member D

Notch-IC — Receptor intracellular domain

NY-ESO-1 — New York esophagus 1 antigen

PD-1 — Programmed cell death protein 1

PD-L1 — Programmed death ligand 1

PGE2 — Prostaglandin E2

PSA — Prostate specific antigen

PTCH — Patched

R — Recombining binding protein suppressor of hairless

Runx2 — Runt-related transcription factor 2

SMO — Smoothened

STAT3 — Signal transducer and activator of transcription 3

SVV-1 — Survivin 1

TAA — Tumor associated antigen

TCF — T-cell factor-1

TGF-β1 — Tumor growth factor beta 1

Treg — T regulatory cell


 

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