The ethics of randomized trials in oncology

BRAF targets in melanoma. Biological mechanisms, resistance, and drug discovery. Cancer drug discovery and development. Volume 82. Ed. Ryan J. Sullivan. Springer (2015)


  1. Introduction
  2. A brief history of clinical research in humans: selected examples
  3. Ethical guidelines for clinical research
  4. Clinical trials: research questions and study design
  5. Ethical issues in the conduct of clinical trials
  6. Special issues in oncology clinical trials
  7. Case study: ethical issues in the BRIM-3 trial
  8. References

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